Open research
Research projects
Each project is a research report plus every source it used, with a clear account of where the evidence comes from and where it stops. Everything lives in the MSRA Open Research knowledge base.
Choose launch notices across species or updates on a specific research topic.
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Referenced publications
Browse the bibliographies behind the reports. Reference numbers follow each project's source list. These include reviews and work in other species or laboratory tissues; read the report for what each publication can establish.
Rabbit digestion and weather40 publications
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1
Lactating performance, water and feed consumption of rabbit does reared under a Mediterranean summer circadian cycle of temperature v. comfort temperature conditions
Bakr MH, Tusell L, Rafel O, et al. · Animal, 2015
Population or scope: Breeding does (farm)
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2
Dietary Betaine improves the intestinal health and growth performance of heat-stressed growing rabbits in summer
Chen X, Li Z, Pu J, et al. · Journal of Animal Science, 2023
Population or scope: Growing rabbits (farm)
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3
Betaine addition to the diet alleviates intestinal injury in growing rabbits during the summer heat through the AAT/mTOR pathway
Li Z, Pu J, Chen X, et al. · Journal of Animal Science and Biotechnology, 2024
Population or scope: Growing rabbits (farm)
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4
Effects of Dietary Supplementations of Vitamin C, Organic Selenium, Betaine, and Pomegranate Peel on Alleviating the Effect of Heat Stress on Growing Rabbits
Abu Hafsa SH, Centoducati G, Hassan AA, et al. · Animals, 2024
Population or scope: Growing rabbits (farm)
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5
Effects of betaine on growth performance and intestinal health of rabbits fed different digestible energy diets
Li Z, Pu J, Zeng T, et al. · Journal of Animal Science, 2024
Population or scope: Growing rabbits (farm)
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6
Impact of Salix mucronata bark and betaine as natural alleviators on semen quality, serum biochemistry, and oxidative capacity in heat-stressed rabbit bucks
Farag MFM, Daader AH, El-Darawany AA, et al. · Tropical Animal Health and Production, 2025
Population or scope: Adult bucks (farm)
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7
Enhancing growing rabbit heat stress resilience through dietary supplementation with natural antioxidants
El-Ratel IT, Mekawy A, Hassab SHM, et al. · BMC Veterinary Research, 2025
Population or scope: Growing rabbits (farm)
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8
Essential Oil Blend and Ascorbic Acid Supplementation Improves Performance, Semen Characteristics, Redox Balance, and Intestinal Integrity in Heat-Stressed Male Rabbits
Alqhtani HA, Alqahtani HA, Elbaz AM, et al. · Veterinary Sciences, 2026
Population or scope: Adult bucks (farm)
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9
An integrated in vitro antioxidant/in vivo metabolomics approach unravels the synergistic effects between oregano essential oil and vitamin C as a nutritional strategy for alleviating heat stress in rabbits
Sayedahmed MM, Safwat AM, Madkour M, et al. · Journal of Animal Science, 2026
Population or scope: Adult male rabbits (farm)
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10
Impacts of Heat Stress on Rabbit Immune Function, Endocrine, Blood Biochemical Changes, Antioxidant Capacity and Production Performance, and the Potential Mitigation Strategies of Nutritional Intervention
Liang ZL, Chen F, Park S, et al. · Frontiers in Veterinary Science, 2022
Population or scope: Review (rabbits)
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11
Drinking Warm Water Improves Growth Performance and Optimizes the Gut Microbiota in Early Postweaning Rabbits during Winter
Wang Q, Fu W, Guo Y, et al. · Animals, 2019
Population or scope: Weaned rabbits (farm)
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12
Hydro-alcoholic extract of Matricaria recutita exhibited dual anti-spasmodic effect via modulation of Ca(2+) channels, NO and PKA(2)-kinase pathway in rabbit jejunum
Yazdi H, Seifi A, Changizi S, et al. · Avicenna Journal of Phytomedicine, 2017
Population or scope: Rabbit gut tissue
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13
Antispasmodic and Antidiarrheal Activities of Valeriana hardwickii Wall. Rhizome Are Putatively Mediated through Calcium Channel Blockade
Bashir S, Memon R, Gilani AH · Evidence-Based Complementary and Alternative Medicine, 2011
Population or scope: Rabbit gut tissue; mice
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14
Protective effect of valerian extract capsule (VEC) on ethanol- and indomethacin-induced gastric mucosa injury and ameliorative effect of VEC on gastrointestinal motility disorder
Feng Y, Dai W, Ke J, et al. · Pharmaceutical Biology, 2022
Population or scope: Rabbit gut tissue; rats; mice
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15
Digestive problems in rabbit production: moving in the wrong direction?
van der Sluis M, van Zeeland YRA, de Greef KH · Frontiers in Veterinary Science, 2024
Population or scope: Review (farmed rabbits)
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16
Health and welfare of rabbits farmed in different production systems
EFSA Panel on Animal Health and Welfare (AHAW), Saxmose Nielsen S, Alvarez J, et al. · EFSA Journal, 2020
Population or scope: Review (farmed rabbits)
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17
The effects of elevated temperature and humidity on rectal temperature and respiration rate in the New Zealand white rabbit
Kasa W, Thwaites CJ · International Journal of Biometeorology, 1990
Population or scope: Adult rabbits (laboratory)
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18
Comparison of the fecal microbiota of domestic commercial meat, laboratory, companion, and shelter rabbits (Oryctolagus cuniculi)
Kylie J, Weese JS, Turner PV · BMC Veterinary Research, 2018
Population or scope: Farm, laboratory, companion and shelter rabbits
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19
Influence of Moringa oleifera extract, vitamin C, and sodium bicarbonate on heat stress-induced HSP70 expression and cellular immune response in rabbits
Abdel-Latif M, Sakran T, Badawi YK, et al. · Cell Stress & Chaperones, 2018
Population or scope: Heat-stressed rabbits (experimental)
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20
Comparing different water supplementation in cyclic heat stressed broilers. The effect of selected antioxidant mixtures, betaine, functional amino acids and electrolyzed reduced water
De Baets R, Van Nerom S, Buyse K, et al. · Poultry Science, 2026
Population or scope: Broilers
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21
Screening of Organic Acid Type and Dosage in Drinking Water for Young Rabbits
Ramón-Moragues A, Vaggi CM, Franch-Dasí J, et al. · Animals, 2024
Population or scope: Weaned rabbits (farm)
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22
Use of Cool Drinking Water as a Strategy Under High-Ambient-Temperature Conditions in New Zealand Rabbits: Growth Performance, Carcass Traits and Physiological Responses
Molina-Gámez G, Robles-Estrada JC, Sánchez-Pérez JN, et al. · Veterinary Sciences, 2026
Population or scope: Growing rabbits (farm)
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23
Organic Selenium, Probiotics, and Prebiotics Effects on Growth, Blood Biochemistry, and Carcass Traits of Growing Rabbits During Summer and Winter Seasons
Ayyat MS, Al-Sagheer AA, Abd El-Latif KM, et al. · Biological Trace Element Research, 2018
Population or scope: Growing rabbits (farm)
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24
Seasonal Variations in Production Performance, Health Status, and Gut Microbiota of Meat Rabbit Reared in Semi-Confined Conditions
Ye D, Ding X, Pang S, et al. · Animals, 2023
Population or scope: Growing rabbits (farm)
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25
Clinical characteristics and short-term outcomes for rabbits with signs of gastrointestinal tract dysfunction: 117 cases (2014-2016)
Oparil KM, Gladden JN, Babyak JM, et al. · Journal of the American Veterinary Medical Association, 2019
Population or scope: Pet rabbits (hospital)
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26
Prognostic value of rectal temperature at hospital admission in client-owned rabbits
Di Girolamo N, Toth G, Selleri P · Journal of the American Veterinary Medical Association, 2016
Population or scope: Pet rabbits (hospital)
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27
Dietary fibres in the nutrition of the growing rabbit and recommendations to preserve digestive health: a review
Gidenne T · Animal, 2015
Population or scope: Review (growing rabbits)
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28
Inter-relationship of microbial activity, digestion and gut health in the rabbit: effect of substituting fibre by starch in diets having a high proportion of rapidly fermentable polysaccharides
Gidenne T, Jehl N, Lapanouse A, et al. · British Journal of Nutrition, 2004
Population or scope: Young rabbits (experimental)
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29
Food and water intake and selective feeding in rabbits on four feeding regimes
Prebble JL, Meredith AL · Journal of Animal Physiology and Animal Nutrition, 2014
Population or scope: Dutch rabbits on pet diets
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30
Effect of a starter diet supplementation with mannan-oligosaccharide or inulin on health status, caecal metabolism, digestibility of nutrients and growth of early weaned rabbits
Volek Z, Marounek M, Skřivanová V · Animal, 2007
Population or scope: Weaned rabbits (farm)
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31
Effects of probiotic Enterococcus faecium and Saccharomyces cerevisiae on the faecal microflora of pet rabbits
Benato L, Hastie P, O'Shaughnessy P, et al. · Journal of Small Animal Practice, 2014
Population or scope: Pet rabbits
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32
Synbiotics are Better Than Probiotics and Prebiotics for Use as Nutrition in Growing Rabbits
Alrajab K, Ghoorchi T, Toghdory A, et al. · Veterinary Medicine and Science, 2026
Population or scope: Weaned rabbits (farm)
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33
Effects of probiotic supplement (Bacillus subtilis and Lactobacillus acidophilus) on feed efficiency, growth performance, and microbial population of weaning rabbits
Phuoc TL, Jamikorn U · Asian-Australasian Journal of Animal Sciences, 2017
Population or scope: Weaned rabbits (farm)
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34
Effects of Dietary Supplementation of Lactobacillus acidophilus on Blood Parameters and Gut Health of Rabbits
Colombino E, Biasato I, Michetti A, et al. · Animals, 2022
Population or scope: Growing rabbits (farm)
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35
Effect of rabbit gastrointestinal stasis (RGIS) on the fecal microbiota of pet rabbits (Oryctolagus cuniculus)
Rahic-Seggerman FM, Iske C, Graham J, et al. · PLoS One, 2025
Population or scope: Pet rabbits
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36
Verification of the Utility of the Standardized Melissa officinalis Extract to Control Gut Contractility in Sheep-Ex Vivo Study
Posłuszny MA, Chłopecka-Słomińska M, Cherer SS, et al. · Animals, 2025
Population or scope: Sheep gut tissue
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37
Evidence Supports Tradition: The in Vitro Effects of Roman Chamomile on Smooth Muscles
Sándor Z, Mottaghipisheh J, Veres K, et al. · Frontiers in Pharmacology, 2018
Population or scope: Guinea pig, rat and human gut tissue
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38
The 4 prokinetic drugs metoclopramide, cisapride, pyridostigmine, and capromorelin do not increase fecal output or food intake in healthy New Zealand rabbits (Oryctolagus cuniculus)
Di Girolamo N, Maranville RE, Pathak D, et al. · Journal of the American Veterinary Medical Association, 2025
Population or scope: Healthy laboratory rabbits
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39
Morbidity and mortality of domestic rabbits (Oryctolagus cuniculus) under primary veterinary care in England
O'Neill DG, Craven HC, Brodbelt DC, et al. · Veterinary Record, 2020
Population or scope: Pet rabbits (primary-care records)
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40
Diagnosis and clinical management of gastrointestinal conditions in exotic companion mammals (rabbits, guinea pigs, and chinchillas)
Ritzman TK · Veterinary Clinics of North America: Exotic Animal Practice, 2014
Population or scope: Review (rabbits and other small herbivores)
Feline urinary health41 publications
Read the report →
Original numbered bibliography →
41-source index with access and evidence limits →
Public report references 1–40, with the locally added 2025 iCatCare consensus guideline shown separately as reference 41.
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1
Starch to protein ratio and food moisture content influence water balance and urine supersaturation in cats
Gonçalves Tozato ME, de Souza Theodoro S, Warde Luis L, et al. · PLoS One, 2024
Population or scope: Healthy cats
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2
The effect of changing the moisture levels of dry extruded and wet canned diets on physical activity in cats
Thomas DG, Post M, Bosch G · Journal of Nutritional Science, 2017
Population or scope: Healthy cats
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3
Increasing dietary sodium chloride promotes urine dilution and decreases struvite and calcium oxalate relative supersaturation in healthy dogs and cats
Queau Y, Bijsmans ES, Feugier A, et al. · Journal of Animal Physiology and Animal Nutrition, 2020
Population or scope: Healthy cats and dogs
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4
Increasing Dietary Potassium Enhances Urine Production and Reduces Risk of Calcium Oxalate Stone Formation in Senior Cats
Hall JA, Yu S, Toillion AR, et al. · Animals, 2026
Population or scope: Healthy senior cats
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5
Cardiovascular effects of dietary salt intake in aged healthy cats: a 2-year prospective randomized, blinded, and controlled study
Chetboul V, Reynolds BS, Trehiou-Sechi E, et al. · PLoS One, 2014
Population or scope: Healthy aged cats
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6
Quantified water intake in laboratory cats from still, free-falling and circulating water bowls, and its effects on selected urinary parameters
Robbins MT, Cline MG, Bartges JW, et al. · Journal of Feline Medicine and Surgery, 2019
Population or scope: Healthy laboratory cats
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7
Effect of water source on intake and urine concentration in healthy cats
Grant DC · Journal of Feline Medicine and Surgery, 2010
Population or scope: Healthy cats (client-owned)
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8
A diet with a struvite relative supersaturation less than 1 is effective in dissolving struvite stones in vivo
Houston DM, Weese HE, Evason MD, et al. · British Journal of Nutrition, 2011
Population or scope: Cats with struvite stones
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9
Efficacy of two commercially available, low-magnesium, urine-acidifying dry foods for the dissolution of struvite uroliths in cats
Lulich JP, Kruger JM, Macleay JM, et al. · Journal of the American Veterinary Medical Association, 2013
Population or scope: Cats with struvite stones
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10
Initial treatment factors associated with feline urethral obstruction recurrence rate: 192 cases (2004-2010)
Hetrick PF, Davidow EB · Journal of the American Veterinary Medical Association, 2013
Population or scope: Cats with urethral obstruction
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11
Effect of prazosin on feline recurrent urethral obstruction
Hanson KR, Rudloff E, Yuan L, et al. · Journal of Feline Medicine and Surgery, 2021
Population or scope: Cats with urethral obstruction
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12
The effect of prazosin on outcome in feline urethral obstruction
Reineke EL, Thomas EK, Syring RS, et al. · Journal of Veterinary Emergency and Critical Care, 2017
Population or scope: Cats with urethral obstruction
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13
Evaluation of meloxicam for the treatment of obstructive feline idiopathic cystitis
Dorsch R, Zellner F, Schulz B, et al. · Journal of Feline Medicine and Surgery, 2016
Population or scope: Cats with obstructive idiopathic cystitis
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14
Efficacy of intravesical pentosan polysulfate sodium in cats with obstructive feline idiopathic cystitis
Delille M, Fröhlich L, Müller RS, et al. · Journal of Feline Medicine and Surgery, 2016
Population or scope: Cats with obstructive idiopathic cystitis
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15
Intravesical application of lidocaine and sodium bicarbonate in the treatment of obstructive idiopathic lower urinary tract disease in cats
Zezza L, Reusch CE, Gerber B · Journal of Veterinary Internal Medicine, 2012
Population or scope: Cats with obstructive idiopathic lower urinary tract disease
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16
Lorazepam reduces recurrence of urethral obstruction in male cats: a prospective, randomized, double-blinded, placebo-controlled study
Splittstoesser A, Kerley J, Lulich J, et al. · Journal of the American Veterinary Medical Association, 2026
Population or scope: Cats with urethral obstruction (client-owned)
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17
Companion Animals Symposium: dietary management of feline lower urinary tract symptoms
Kerr KR · Journal of Animal Science, 2013
Population or scope: Review
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18
Cats and calcium oxalate: strategies for managing lower and upper tract stone disease
Palm C, Westropp J · Journal of Feline Medicine and Surgery, 2011
Population or scope: Review
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19
Nutritional Management of Urolithiasis
Queau Y · Veterinary Clinics of North America: Small Animal Practice, 2019
Population or scope: Review (dogs and cats)
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20
Diet format, protein, amino acids, salt, and osmolytes, as well as water viscosity, affect water consumption in domestic cats: a scoping review of 32 publications (published from 1975 to 2025) on water intake, hydration status, and related health outcomes
Kosmal PAL, Shoveller AK, Gillies G, et al. · Journal of Animal Science, 2026
Population or scope: Review (scoping review of 32 cat studies)
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21
Effect of dietary water intake on urinary output, specific gravity and relative supersaturation for calcium oxalate and struvite in the cat
Buckley CM, Hawthorne A, Colyer A, et al. · British Journal of Nutrition, 2011
Population or scope: Healthy cats
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22
Increasing Dietary Potassium Chloride Promotes Urine Dilution and Decreases Calcium Oxalate Relative Supersaturation in Healthy Dogs and Cats
Bijsmans E, Quéau Y, Biourge V · Animals, 2021
Population or scope: Healthy cats and dogs
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23
Increased Water Viscosity Enhances Water Intake and Reduces Risk of Calcium Oxalate Stone Formation in Cats
Hall JA, Vanchina MA, Ogleby B, et al. · Animals, 2021
Population or scope: Healthy cats
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24
Effects of a nutrient-enriched water on water intake and indices of hydration in healthy domestic cats fed a dry kibble diet
Zanghi BM, Gerheart L, Gardner CL · American Journal of Veterinary Research, 2018
Population or scope: Healthy cats
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25
Clinical evaluation of commercially available urinary acidification diets in the management of idiopathic cystitis in cats
Markwell PJ, Buffington CA, Chew DJ, et al. · Journal of the American Veterinary Medical Association, 1999
Population or scope: Cats with idiopathic cystitis (client-owned)
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26
Understanding the current evidence base for the commonly recommended management strategies for recurrent feline idiopathic cystitis: a systematic review
Macleod B, Laven LJ, Laven RA, et al. · New Zealand Veterinary Journal, 2025
Population or scope: Review (systematic review)
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27
Effect of a struvite dissolution diet in cats with naturally occurring struvite urolithiasis
Tefft KM, Byron JK, Hostnik ET, et al. · Journal of Feline Medicine and Surgery, 2021
Population or scope: Cats with struvite stones (client-owned)
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28
The effect of diet on lower urinary tract diseases in cats
Markwell PJ, Buffington CT, Smith BH · Journal of Nutrition, 1998
Population or scope: Review
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29
Effects of dietary sodium chloride on health parameters in mature cats
Xu H, Laflamme DP, Long GL · Journal of Feline Medicine and Surgery, 2009
Population or scope: Healthy mature cats
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30
Short term effects of increasing dietary salt concentrations on urine composition in healthy cats
Paßlack N, Burmeier H, Brenten T, et al. · Veterinary Journal, 2014
Population or scope: Healthy cats
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31
Prazosin administration increases the rate of recurrent urethral obstruction in cats: 388 cases
Conway DS, Rozanski EA, Wayne AS · Journal of the American Veterinary Medical Association, 2022
Population or scope: Cats with urethral obstruction
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32
A prospective randomized study of efficacy of 2 treatment protocols in preventing recurrence of clinical signs in 51 male cats with obstructive idiopathic cystitis
Nivy R, Segev G, Rimer D, et al. · Journal of Veterinary Internal Medicine, 2019
Population or scope: Cats with obstructive idiopathic cystitis
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33
Intravesical glycosaminoglycans for obstructive feline idiopathic cystitis: a pilot study
Bradley AM, Lappin MR · Journal of Feline Medicine and Surgery, 2014
Population or scope: Cats with urethral obstruction (client-owned)
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34
Effect of intraurethral administration of atracurium besylate in male cats with urethral plugs
Galluzzi F, De Rensis F, Menozzi A, et al. · Journal of Small Animal Practice, 2012
Population or scope: Cats with urethral plugs
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35
Evaluation of the efficacy of a commercial diet in the dissolution of feline struvite bladder uroliths
Houston DM, Rinkardt NE, Hilton J · Veterinary Therapeutics, 2004
Population or scope: Cats with struvite stones
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36
Comparison of foods with differing nutritional profiles for long-term management of acute nonobstructive idiopathic cystitis in cats
Kruger JM, Lulich JP, MacLeay J, et al. · Journal of the American Veterinary Medical Association, 2015
Population or scope: Cats with non-obstructive idiopathic cystitis
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37
The effect of a therapeutic urinary stress diet on the short-term recurrence of feline idiopathic cystitis
Naarden B, Corbee RJ · Veterinary Medicine and Science, 2020
Population or scope: Cats with non-obstructive idiopathic cystitis
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38
Relative supersaturation values distinguish between feline urinary and non-urinary foods and align with expected urine analytes contributions to uroliths
Morris EM, McGrath AP, Brejda J, et al. · Frontiers in Veterinary Science, 2023
Population or scope: Healthy cats
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39
A new diet supplement formulation containing cranberry extract for the treatment of feline idiopathic cystitis
Colombino E, Cavana P, Martello E, et al. · Natural Product Research, 2022
Population or scope: Cats with idiopathic cystitis (client-owned)
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40
A placebo-controlled study of an herbal compound used for management of lower urinary tract disease in healthy cats
Martin CE, Bartges JW, English CF, et al. · Frontiers in Veterinary Science, 2026
Population or scope: Healthy cats
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41
2025 iCatCare consensus guidelines on the diagnosis and management of lower urinary tract diseases in cats
Taylor S, Boysen S, Buffington T, et al. · Journal of Feline Medicine and Surgery, 2025
Population or scope: Clinical consensus guideline (cats)
A full-text link records availability, not a completed appraisal or clinical recommendation.